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| Brandon Davis Educational Background: 1992-1997 Northwestern University (Evanston, IL) Ph.D. December 1997 Department of Molecular Pharmacology and Biological Chemistry1 Integrated Graduate Program in the Life Sciences 1988-1992 Northwestern College of Iowa (Orange City, IA) Bachelor of Arts, Biology/Health Sciences summa cum laude 1987-1988 Dordt College (Sioux Center, IA) Professional memberships:2 American Association for the Advancement of Science Sigma Xi Scientific Research Society Research Experience:3 1999-present4 Research Associate. Genetic analysis of mutations causing hormone-independent signaling of the human luteinizing hormone receptor, Adviser's name. Children's Memorial Hospital (Department of Endocrinology) and Northwestern University Medical School (Department of Pediatrics), Chicago, IL. 1997-1999 Postdoctoral Fellow. Functional analysis of the proteasome, the central protease of cell cycle and growth control, Adviser's name. Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL. 1993-1997 Doctoral student. Regulation of m2 muscarinic acetylcholine receptor desensitization by phosphorylation. Adviser's name. Department of Molecular Pharmacology and Biological Chemistry, Northwestern University Medical School, Chicago, IL. 1992 Identification of angiogenic factors and Rb-induced anti-angiogenic factors in retinoblastoma cells. Adviser's name. Department of Microbiology and Immunology, Northwestern University Medical School, Chicago, IL. 1991 Development of an ELISA assay for measurement of maternal anti-Hemophilus antibody in newborn swine. Supervisor's name. NOBL Laboratories, Sioux Center, IA. Teaching experiences: 1999 Adjunct instructor, Trinity Christian College, Palos Heights, IL --Introductory Biology with laboratory (cell biology, genetics, evolution) Fall 1999 --Genetics with laboratory Spring 2000 1993 Teaching assistant, Northwestern University Integrated Graduate Program in the Life Sciences, Graduate Molecular Biology I. Attended lectures, conducted twice-weekly review and discussion sessions, wrote test questions and graded exams. Informal teaching activities: 1998 Private tutor, University of Chicago laboratory secondary school. --Freshman biology (student with learning disability) --AP chemistry (private lessons in college-level chemistry) 1997 Guest lecturer, Northwestern College, IA, Biochemistry class. 1995 Substitute lecturer, National Louis University, General biology 1995 Supervised first-year graduate student in 12-week research project 1994 Private tutor, Northwestern University Graduate Molecular Biology I. 1991 Lab assistant, Northwestern College, IA, Microbiology. Prepared lab reagents, answered questions during lab sessions, graded papers and quizzes. Awards and Fellowships: 1998-2001 American Cancer Society postdoctoral fellowship 1997-1998 Postdoctoral traineeship, Cancer Biology Training Grant, University of Chicago 1992-1997 Howard Hughes Medical Institute Predoctoral Fellowship 1996, 1994 Student Travel Fellowships, International Symposia on Subtypes of Muscarinic Receptors 1996 Best student poster award, Chicago Signal Transduction Symposium 1995, 1997 Best student poster award, Great Lakes Chapter of the American Society for Pharmacology and Experimental Therapeutics 1995 Finalist, Northwestern University Sigma Xi research presentation competition 1992 Faculty honors, Northwestern College, IA (awarded to two graduates each year) Other activities and honors: 1998-1999 Freezer manager, University of Chicago-MBI Fermentas enzyme freezer program. --procured a lab discount on restriction enzymes in exchange for stocking and monitoring inventory in an on-site supply freezer 1998 "The Epic of Creation" lecture series, Chicago Center for Religion and Science/Lutheran School of Theology Chicago 1997 Homecoming alumni speaker, Northwestern College, IA 1992 NAIA All-America, Volleyball and Track/Field 1991 GTE-CoSIDA Academic All-American and player of the year, volleyball Refereed Publications: 1. Author, co-authors. "Desensitization and Internalization of the m2 Muscarinic Acetylcholine Receptor are Directed by Independent Mechanisms." Journal of Biological Chemistry 270: 29004-2901, 1995. 2. Author, co-authors. "Two Homologous Phosphorylation Domains Differentially Contribute to Desensitization and Internalization of the m2 Muscarinic Acetylcholine Receptor." Journal of Biological Chemistry 272: 14152-14158, 1997. 3. Author, co-authors. "Internalization of the m2 Muscarinic Acetylcholine Receptor: Arrestin-independent and -dependent pathways." Journal of Biological Chemistry 272: 23682-23689, 1997. 4. Author, co-authors. "Agonist-receptor-arrestin: An alternative ternary complex with high agonist affinity." Journal of Biological Chemistry 272: 28849-28852, 1997. 5. Author, co-authors. "Arrestin-independent Internalization of the m1, m3, and m4 subtypes of Muscarinic Cholinergic Receptors. Journal of Biological Chemistry 271: 12967-12972, 1998. Invited Reviews: 1. Author, co-authors. Molecular events associated with the regulation of signaling by M2 muscarinic receptors. Life Sciences, 64: 363-8, 1999 2. Author. Quick Guide: The Proteasome. Current Biology 8: R902, 1998. 3. Author, co-authors. Desensitization of G-protein coupled receptors in the cardiovascular system. Annual Review of Physiology, 61: 169-92, 1999. 4. Author, co-authors. "Tbe Role of G-protein Coupled Receptor Kinases in the Regulation of Muscarinic Acetylcholine Receptors" in Cholinergic Mechanisms: From Molecular Biology to Clinical Significance (Proceedings of the Ninth International Symposium on Cholinergic Mechanisms), Progress in Brain Research (1996), K. Loffelholz and J. Klein, eds., Elsevier. Selected abstracts (national and international meetings): 1. Author, co-author. (1996) Agonist-dependent phosphorylation of the m2 muscarinic acetylcholine receptor: Two phosphorylation domains possess distinct regulatory roles. Seventh International Symposium on Subtypes of Muscarinic Receptors. Vienna, VA. 2. Author, co-author. (1996) Agonist-dependent phosphorylation of the m2 muscarinic acetylcholine receptor: Two phosphorylation domains possess distinct regulatory roles. ASBMB Fall Symposium, Molecular Recognition in G Protein Signaling. Keystone, CO. 3. Author, co-author. (1995) G-protein coupled receptor kinase activity is required for rapid desensitization of the m2 muscarinic acetylcholine receptor but not for receptor sequestration. Ninth International Conference on Second Messengers and Phosphoproteins. Vanderbilt University, Nashville, TN. 4. Author, co-author. (1994) Muscarinic acetylcholine receptor desensitization: effects of dominant-negative bARK1. International Symposium on Subtypes of Muscarinic Receptors, Fort Lauderdale, FL. Selected seminars: 1. "Suppressors of mutation in sen3, an essential proteasome regulatory subunit." University of Chicago yeast group seminar series, June 1998. 2. "Allosterism and protein-protein interactions in regulation of G-protein coupled receptors." Northwestern College (IA) invited lecture, October 1997. 3. "Agonist-dependent phosphorylation of the m2 muscarinic acetylcholine receptor: Two phosphorylation domains possess distinct regulatory roles." Seventh International Symposium on Subtypes of Muscarinic Receptors, November, 1996. 4. "Functional and structural basis for m2 muscarinic acetylcholine receptor desensitization." Howard Hughes Medical Institute Predoctoral and Physician Postdoctoral Fellows meeting, June 1996. 5. "Receptor desensitization in cardiac regulation", Northwestern College (IA) biology department seminar series, March 1995. 6. "Role of G-protein coupled receptor kinases in m2 muscarinic acetylcholine receptor desensitization." Northwestern University Sigma Xi competition, April 1995. 7. Annually presented a formal department seminar at Northwestern University Department of Molecular Pharmacology and Biological Chemistry. References: Post doctoral adviser, University, Address, City, State, Zip Code. (999) 999-9999. Doctoral Adviser, Medical School, Address, City, State, Zip Code. (999) 999-9999. | |
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